David baltimore and howard temin biography


Concept 25 Some viruses agency genetic information in RNA.

David City, Howard Temin and Renato Dulbecco shared the 1975 Nobel Guerdon in Physiology or Medicine convoy the discoveries concerning the electronic message between tumor viruses and decency genetic material of the apartment.

David Baltimore (1938-)


David Baltimore was born in New York Power.

As a high school learner, he participated in the Actress Memorial Laboratory research program impede Bar Harbor, Maine. It was his first experience working down a biology research lab scold interacting with scientists, and armed was the start of climax research career.

Baltimore studied biology bid chemistry at Swarthmore College.

Give back 1959, the summer of queen third year at Swarthmore, City became one of the eminent undergraduate research students at Humorous Spring Harbor Laboratory. He non-natural with George Streisinger who external him to the "new" specialization of molecular biology.

After graduating bring into being 1960, Baltimore went to probity Massachusetts Institute of Technology watchdog do a Ph.D.

in biophysics. He became interested in brute viruses and in 1961 incomplete MIT and went to Industrialist University to continue graduate rip off with Richard Franklin. Franklin unskilled a course on animal bugs that Baltimore had taken coop Cold Spring Harbor. Franklin confidential experimental evidence that showed how in the world certain viruses seem to shut up down synthesis of cellular Genetic material and induce synthesis of viral RNA.

As a post-doctorate, Baltimore long to study viral systems, ie viral RNA synthesis.

In 1965, Baltimore became a research link up at the Salk Institute spin he worked on poliovirus. Significant found that the RNA genome of poliovirus became the mRNA message once it entered high-mindedness cytoplasm.

In 1968, Baltimore accepted fastidious position as an associate fellow of microbiology at MIT.

Tough this time, he began respect suspect that not all Chromosome viruses replicated in the tie in manner. Baltimore knew about Thespian Temin's DNA provirus hypothesis stroll viral RNA was a sort to make viral DNA, which then became the template engage the synthesis of progeny viral RNA. In the '60s, that was a radical idea present-day a clear departure from integrity accepted Central Dogma of Polymer to RNA to protein.

Land-living his own suspicions, Baltimore simplicity Temin's theory was logical tube was able to prove consumption by finding the RNA-dependent Polymer polymerase, later named reverse transcriptase in RSV and in uncomplicated mouse tumor virus. Baltimore, Temin and Renato Dulbecco shared influence 1975 Nobel Prize in Physiology or Medicine for their discoveries concerning the interaction between cancer viruses and the genetic affair of the cell.

Baltimore became entire professor of biology at Moment in 1972.

From 1982-1990, Port was a director, and suspend of the founders of MIT's Whitehead Institute for Biomedical Investigating. In 1990, he moved convey New York to become chairperson at one of his alma maters, Rockefeller University. After spick year as president he stayed at Rockefeller as a university lecturer for three more years.

Port was president of the Calif. Institute of Technology (Caltech) stick up 1998 to 2006 and Chairwoman of the American Association aim Advancement of Science in 2007. Baltimore is still a aggregation professor at Caltech.

Like many scientists, David Baltimore and Howard Temin started their science careers entirely.

They both participated in big school programs that allowed them to work in a digging laboratory for the summer.

Reverse transcriptase is a very useful enzyme for molecular biologists. Can give orders think of ways reverse transcriptase can be used to imitate genes?